Publications

Nature Genetics Paper

(2018) A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Nat.Genet. Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley MA Jr, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN, den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH, Hewitt AW, Swaroop A, Chew EY, Pericak- Vance MA, DeAngelis M, Stambolian D, Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM.

(2013) Seven new loci associated with age-related macular degeneration.Nat. Genet. Fritsche, LG, Chen, W, Schu, M, Yaspan, BL, Yu, Y, Thorleifsson, G, Zack, DJ, Arakawa, S, Cipriani, V, Ripke, S, Igo, RP Jr, Buitendijk, GH, Sim, X, Weeks, DE, Guymer, RH, Merriam, JE, Francis, PJ, Hannum, G, Agarwal, A, Armbrecht, AM, Audo, I, Aung, T, Barile, GR, Benchaboune, M, Bird, AC, Bishop, PN, Branham, KE, Brooks, M, Brucker, AJ, Cade, WH, Cain, MS, Campochiaro, PA, Chan, CC, Cheng, CY, Chew, EY, Chin, KA, Chowers, I, Clayton, DG, Cojocaru, R, Conley, YP, Cornes, BK, Daly, MJ, Dhillon, B, Edwards, AO, Evangelou, E, Fagerness, J, Ferreyra, HA, Friedman, JS, Geirsdottir, A, George, RJ, Gieger, C, Gupta, N, Hagstrom, SA, Harding, SP, Haritoglou, C, Heckenlively, JR, Holz, FG, Hughes, G, Ioannidis, JP, Ishibashi, T, Joseph, P, Jun, G, Kamatani, Y, Katsanis, N, N Keilhauer, C, Khan, JC, Kim, IK, Kiyohara, Y, Klein, BE, Klein, R, Kovach, JL, Kozak, I, Lee, CJ, Lee, KE, Lichtner, P, Lotery, AJ, Meitinger, T, Mitchell, P, Mohand-Saïd, S, Moore, AT, Morgan, DJ, Morrison, MA, Myers, CE, Naj, AC, Nakamura, Y, Okada, Y, Orlin, A, Ortube, MC, Othman, MI, Pappas, C, Park, KH, Pauer, GJ, Peachey, NS, Poch, O, Priya, RR, Reynolds, R, Richardson, AJ, Ripp, R, Rudolph, G, Ryu, E, Sahel, JA, Schaumberg, DA, Scholl, HP, Schwartz, SG, Scott, WK, Shahid, H, Sigurdsson, H, Silvestri, G, Sivakumaran, TA, Smith, RT, Sobrin, L, Souied, EH, Stambolian, DE, Stefansson, H, Sturgill-Short, GM, Takahashi, A, Tosakulwong, N, Truitt, BJ, Tsironi, EE, Uitterlinden, AG, van Duijn, CM, Vijaya, L, Vingerling, JR, Vithana, EN, Webster, AR, Wichmann, HE, Winkler, TW, Wong, TY, Wright, AF, Zelenika, D, Zhang, M, Zhao, L, Zhang, K, Klein, ML, Hageman, GS, Lathrop, GM, Stefansson, K, Allikmets, R, Baird, PN, Gorin, MB, Wang, JJ, Klaver, CC, Seddon, JM, Pericak-Vance, MA, Iyengar, SK, Yates, JR, Swaroop, A, Weber, BH, Kubo, M, Deangelis, MM, Léveillard, T, Thorsteinsdottir, U, Haines, JL, Farrer, LA, Heid, IM, Abecasis, GR, AMD Gene Consortium

Supplemental information

Materials for recent Nature Genetics publication submission

Recent Publications on PubMed

  1. (2019) Insights into the loss of the Y chromosome with age in control individuals and in patients with age-related macular degeneration using genotyping microarray data.

    Hum. Genet.

    Grassmann, F, International AMD Genomics Consortium (IAMDGC), Weber, BHF, Veitia, RA

  2. (2019) Y chromosome mosaicism is associated with age-related macular degeneration.

    Eur. J. Hum. Genet.

    Grassmann, F, Kiel, C, den Hollander, AI, Weeks, DE, Lotery, A, Cipriani, V, Weber, BHF, International Age-related Macular Degeneration Genomics Consortium (IAMDGC)

  3. (2018) Improved score statistics for meta-analysis in single-variant and gene-level association studies.

    Genet. Epidemiol.

    Yang, J, Chen, S, Abecasis, G, IAMDGC

  4. (2018) Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci.

    PLoS ONE

    Winkler, TW, Brandl, C, Grassmann, F, Gorski, M, Stark, K, Loss, J, Weber, BHF, Heid, IM, International Age-related Macular Degeneration Genomics Consortium (IAMDGC)

  5. (2018) Geographic distribution of rare variants associated with age-related macular degeneration.

    Mol. Vis.

    Geerlings, MJ, Kersten, E, Groenewoud, JMM, Fritsche, LG, Hoyng, CB, de Jong, EK, den Hollander, AI

  6. (2017) Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1.

    Invest. Ophthalmol. Vis. Sci.

    Persad, PJ, Heid, IM, Weeks, DE, Baird, PN, de Jong, EK, Haines, JL, Pericak-Vance, MA, Scott, WK, International Age-Related Macular Degeneration Genomics Consortium (IAMDGC)

  7. (2017) Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

    Genome Med

    Grassmann, F, Kiel, C, Zimmermann, ME, Gorski, M, Grassmann, V, Stark, K, International AMD Genomics Consortium (IAMDGC), Heid, IM, Weber, BH

  8. (2017) Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration.

    Genetics

    Grassmann, F, Heid, IM, Weber, BH, International AMD Genomics Consortium (IAMDGC)

  9. (2016) Genetic Association Analysis of Drusen Progression.

    Invest. Ophthalmol. Vis. Sci.

    Hoffman, JD, van Grinsven, MJ, Li, C, Brantley, M Jr, McGrath, J, Agarwal, A, Scott, WK, Schwartz, SG, Kovach, J, Pericak-Vance, M, Sanchez, CI, Haines, JL

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