{"id":800,"date":"2020-05-27T18:48:22","date_gmt":"2020-05-27T18:48:22","guid":{"rendered":"http:\/\/eaglep.case.edu\/iamdgc_web\/?page_id=800"},"modified":"2025-07-22T21:47:49","modified_gmt":"2025-07-22T21:47:49","slug":"about-2","status":"publish","type":"page","link":"http:\/\/eaglep.case.edu\/iamdgc_web\/?page_id=800","title":{"rendered":"About"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.0.6″ background_color=”rgba(0,0,0,0)” min_height=”126px” height=”206px” max_height=”211px” custom_margin=”3px||-140px||false|false” custom_padding=”6px||6px||false|false” global_colors_info=”{}”][et_pb_fullwidth_header title=”Your Title Goes Here” button_one_text=” ” _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_button_one=”on” button_one_text_color=”rgba(0,0,0,0)” min_height=”249px” custom_margin=”-87px||-126px|||” custom_padding=”9px||0px|||” global_colors_info=”{}”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#006787″ custom_margin=”4px||-87px|||” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.0.6″ custom_padding=”||0px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_divider _builder_version=”4.0.6″ background_color=”#006787″ custom_margin=”-96px|||||” custom_padding=”||0px|||” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#006787″ custom_margin=”||-87px|||” custom_padding=”0px|||0px|false|false” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.0.6″ background_color=”#ffffff” custom_margin=”28px|auto|-76px|auto|false|false” custom_margin_tablet=”|-1px||76px|false|false” custom_margin_phone=”5px||-55px|58px|false|false” custom_margin_last_edited=”on|desktop” custom_padding=”||0px||false|false” global_module=”1013″ saved_tabs=”all” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_image _builder_version=”4.0.6″ custom_margin=”-43px|||||” custom_padding=”|||0px|false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_image src=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2020\/05\/AMD-logo-V6_no-fill_small_no_rim.png” _builder_version=”4.0.6″ custom_margin=”-18px||27px|63px|false|false” custom_margin_tablet=”|0px||157px|false|false” custom_margin_phone=”|||40px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”51px||19px|7px|false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_text _builder_version=”4.0.6″ text_font=”Archivo|700|||||||” custom_margin=”|16px||-45px|false|false” custom_margin_tablet=”|||37px|false|false” custom_margin_phone=”-15px||18px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px|12px|34px||false|false” border_color_all=”#0006787″ global_colors_info=”{}”]<\/p>\n

Defining the genomic architecture of Age-related Macular Degeneration (AMD)\u00a0<\/span><\/strong>to improve diagnosis, treatment, and prevention.<\/span><\/strong><\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_image _builder_version=”4.0.6″ background_color=”#FFFFFF” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ specialty=”on” padding_top_bottom_link_2=”false” padding_left_right_link_2=”false” padding_right_2=”1px” padding_bottom_2=”0px” _builder_version=”4.0.6″ background_color=”#FFFFFF” min_height=”168px” height=”186px” max_height=”186px” custom_margin=”-48px||-2px||false|false” custom_padding=”0px||15px||false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_margin=”|-922px|||false|false” custom_margin_tablet=”|0px|||false|false” custom_margin_phone=”30px||-40px|33px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”48px||0px|20px|false|false” custom_padding_tablet=”||0px||false|false” custom_padding_phone=”||0px||false|false” custom_padding_last_edited=”on|phone” text_font_size_tablet=”” text_font_size_phone=”2px” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

The consortium includes 33 academic and independent research institutes.\u00a0<\/span><\/h2>\n

 <\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ specialty_columns=”2″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_margin=”16px||||false|false” custom_padding=”0px||0px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.0.6″ custom_padding=”1px|||||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_divider _builder_version=”4.0.6″ background_color=”#006787″ custom_padding=”0px||0px||false|false” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|desktop” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_text _builder_version=”4.14.2″ text_font=”Arial||||||||” text_font_size=”13px” custom_padding=”0px||||false|false” text_font_size_tablet=”13px” text_font_size_phone=”13px” text_font_size_last_edited=”on|desktop” text_line_height_tablet=”” text_line_height_phone=”” text_line_height_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

The International AMD Genomics Consortium (IAMDGC) was formed in 2012 to aggregate genetic and genomic data from research groups across the world, with the goal of illuminating the genetic architecture of AMD.<\/h3>\n

The IAMDGC built upon the success of the AMD gene consortium, which started in 2010 under the leadership of Drs. Margaret Pericak-Vance and Jonathan Haines with the support of Dr. Hemin Chin, then the Director, Ocular Genetics and Center Core Grant Programs, Division of Extramural Research, National Eye Institute.<\/h3>\n

The IAMDGC has greatly expanded the number of participating groups, the amount of genetic data, and the analytical methods of analyzing these data. It published the largest AMD GWAS to date, and the data from that GWAS have been used in subsequent publications to identify new loci.<\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|phone” _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_margin=”|||auto|false|false” custom_padding=”17px|0px||0px|false|false” custom_padding_tablet=”|0px||0px|false|false” custom_padding_phone=”” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_image src=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2020\/05\/Map-with-logo-V9.png” show_bottom_space_tablet=”” show_bottom_space_phone=”” show_bottom_space_last_edited=”on|phone” _builder_version=”4.0.6″ custom_margin=”||||false|false” custom_padding=”0px||27px|327px|false|false” custom_padding_tablet=”|||54px|false|false” custom_padding_phone=”|0px||0px|false|false” custom_padding_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ min_height=”290px” custom_margin=”-102px||-96px||false|false” custom_padding=”0px||0px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.0.6″ custom_padding=”76px|||||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_text _builder_version=”4.0.6″ text_font=”Archivo||||||||” custom_margin=”||54px|||” global_colors_info=”{}”]<\/p>\n

\u00a0<\/h3>\n

Our work centers on<\/h3>\n
    \n
  • \n

    Expanding IAMDGC resources and datasets with a focus on family data and diverse genetic ancestry<\/h3>\n<\/li>\n
  • \n

    Expanding the range of clinical diagnostic measures<\/h3>\n<\/li>\n
  • \n

    Using an analytical hub infrastructure to perform detailed analyses of our collective and individual members\u2019 data<\/h3>\n<\/li>\n<\/ul>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#006787″ custom_margin=”16px||||false|false” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.0.6″ custom_padding=”117px|||||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_text _builder_version=”4.0.6″ background_enable_image=”off” height=”204px” max_height=”203px” custom_margin=”-56px||-137px||false|false” border_color_all=”#0C71C3″ global_colors_info=”{}”]<\/p>\n

    Meet our Principal Investigators\u00a0<\/strong><\/span><\/h1>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.0.6″ hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][et_pb_image src=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2025\/07\/IMG_0049_Haines-pillar_BW.jpg” _builder_version=”4.14.2″ hover_enabled=”0″ global_colors_info=”{}” custom_margin=”|154px|||false|false” alt=”Dr Jonathan Haines_bw photo” title_text=”IMG_0049_Haines pillar_BW” sticky_enabled=”0″ max_width=”100%” max_height=”321px”][\/et_pb_image][et_pb_text _builder_version=”4.0.6″ text_font=”Archivo||||||||” global_colors_info=”{}”]<\/p>\n

    Jonathan L. Haines, PhD<\/span><\/h3>\n
    \n

    The Cleveland Institute for Computational Biology at Case Western Reserve University School of Medicine<\/span><\/h3>\n<\/div>\n

    [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_image src=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2020\/05\/Margaret-Pericak-Vance-PhD-Headshot-BW-2-scaled-e1590773259906.jpeg” _builder_version=”4.0.6″ global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.0.6″ text_font=”Archivo||||||||” global_colors_info=”{}”]<\/p>\n

    Margaret (Peggy) Pericak-Vance, PhD<\/span><\/h3>\n
    \n

    John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine<\/span><\/h3>\n<\/div>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_margin=”||-24px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.0.6″ background_color=”#FFFFFF” background_image=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2021\/10\/Try-this-one-scaled.jpg” custom_padding=”||0px|||” border_color_all=”#ffffff” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.0.6″ global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.0.6″ background_color=”#006787″ custom_margin=”||||false|false” custom_padding=”39px|||||” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.0.6″ background_color=”#FFFFFF” custom_margin=”||||false|false” custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding=”|||0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_image src=”http:\/\/eaglep.case.edu\/iamdgc_web\/wp-content\/uploads\/2020\/05\/AMD-logo-V6_no-fill_small_no_rim.png” _builder_version=”4.0.6″ custom_margin=”||||false|false” custom_margin_tablet=”|||89px|false|false” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding=”|80px||72px|false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.0.6″ global_colors_info=”{}”][et_pb_text _builder_version=”4.0.6″ text_font=”Archivo||||||||” custom_margin=”||||false|false” custom_margin_tablet=”” custom_margin_phone=”|||10px|false|false” custom_margin_last_edited=”on|desktop” custom_padding=”|||9px|false|false” global_colors_info=”{}”]<\/p>\n

    Contact us:<\/span><\/h1>\n

    Susan Halloran Blanton, PhD<\/span><\/h3>\n

    Project Manager, IAMDGC<\/span><\/h3>\n

    Email:\u00a0 SBlanton@med.miami.edu<\/span><\/h3>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

    Defining the genomic architecture of Age-related Macular Degeneration (AMD)\u00a0to improve diagnosis, treatment, and prevention.The consortium includes 33 academic and independent research institutes.\u00a0  The International AMD Genomics Consortium (IAMDGC) was formed in 2012 to aggregate genetic and genomic data from research groups across the world, with the goal of illuminating the genetic architecture of AMD. The […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":""},"_links":{"self":[{"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/pages\/800"}],"collection":[{"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=800"}],"version-history":[{"count":102,"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/pages\/800\/revisions"}],"predecessor-version":[{"id":1721,"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=\/wp\/v2\/pages\/800\/revisions\/1721"}],"wp:attachment":[{"href":"http:\/\/eaglep.case.edu\/iamdgc_web\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}